Gene

otulinb

ID
ZDB-GENE-070912-627
Name
OTU deubiquitinase with linear linkage specificity b
Symbol
otulinb Nomenclature History
Previous Names
  • fam105bb
  • si:dkeyp-106c5.3
  • wu:fc69a03
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in protein linear deubiquitination. Predicted to colocalize with LUBAC complex. Human ortholog(s) of this gene implicated in otulipenia. Orthologous to several human genes including OTULIN (OTU deubiquitinase with linear linkage specificity).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With otulinb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
otulipenia Alliance Autoinflammation, panniculitis, and dermatosis syndrome, autosomal recessive 617099
Autoinflammation, panniculitis, and dermatosis syndrome, autosomal dominant 621030
{Immunodeficiency 107, susceptibility to invasive staphylococcus aureus infection} 619986
Associated With otulinb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR023235 FAM105
Family IPR023236 Inactive ubiquitin thioesterase OTULINL
Domain Details Per Protein
Protein Length FAM105 Inactive ubiquitin thioesterase OTULINL
UniProtKB:A0A8M3B0B6 349
UniProtKB:A0A8M2BAN8 409
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA otulinb-203 (1) Ensembl 661 nt
mRNA otulinb-204 (1) Ensembl 906 nt
mRNA otulinb-206 (1) Ensembl 1,761 nt
ncRNA otulinb-003 (1) Ensembl 817 nt
ncRNA otulinb-004 (1) Ensembl 904 nt
ncRNA otulinb-006 (1) Ensembl 764 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations