Gene
dcst2
- ID
- ZDB-GENE-070809-6
- Name
- DC-STAMP domain containing 2
- Symbol
- dcst2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Acts upstream of or within positive regulation of fertilization and regulation of fusion of sperm to egg plasma membrane. Predicted to be located in membrane. Is expressed in sperm. Orthologous to human DCST2 (DC-STAMP domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Cell Surface Receptor and E3 Ligase Protein | Dendritic cell-specific transmembrane protein-like |
---|---|---|---|---|
UniProtKB:A0AB13A7T9 | InterPro | 709 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-24I24 |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001366341 (1) | 2381 nt | ||
Genomic | GenBank:CR388365 (1) | 137882 nt | ||
Polypeptide | UniProtKB:A0AB13A7T9 (1) | 709 aa |
- Binner, M.I., Kogan, A., Panser, K., Schleiffer, A., Deneke, V.E., Pauli, A. (2022) The Sperm Protein Spaca6 is Essential for Fertilization in Zebrafish. Frontiers in cell and developmental biology. 9:806982
- Noda, T., Blaha, A., Fujihara, Y., Gert, K.R., Emori, C., Deneke, V.E., Oura, S., Panser, K., Lu, Y., Berent, S., Kodani, M., Cabrera-Quio, L.E., Pauli, A., Ikawa, M. (2022) Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish. Communications biology. 5:332
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