Gene
dcst1
- ID
- ZDB-GENE-070809-5
- Name
- DC-STAMP domain containing 1
- Symbol
- dcst1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Acts upstream of or within positive regulation of fertilization and response to mechanical stimulus. Predicted to be located in membrane. Is expressed in scale and sperm. Orthologous to human DCST1 (DC-STAMP domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Noda et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-24I24 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068214150 (1) | 2480 nt | ||
| Genomic | GenBank:CR388365 (1) | 137882 nt | ||
| Polypeptide | RefSeq:XP_068070251 (1) |
- Noda, T., Blaha, A., Fujihara, Y., Gert, K.R., Emori, C., Deneke, V.E., Oura, S., Panser, K., Lu, Y., Berent, S., Kodani, M., Cabrera-Quio, L.E., Pauli, A., Ikawa, M. (2022) Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish. Communications biology. 5:332
- Molagoda, I.M.N., Kang, C.H., Lee, M.H., Choi, Y.H., Lee, C.M., Lee, S., Kim, G.Y. (2021) Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis. Biochemical pharmacology. 192:114676
- Kitamura, K.I., Takahira, K., Inari, M., Satoh, Y., Hayakawa, K., Tabuchi, Y., Ohgai, K., Nishiuchi, T., Kondo, T., Mikuni-Takagaki, Y., Chen, W., Hattori, A., and Suzuki, N. (2013) Zebrafish scales respond differently to in vitro dynamic and static acceleration: Analysis of interaction between osteoblasts and osteoclasts. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 166(1):74-80
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