Gene

adam19b

ID
ZDB-GENE-070705-541
Name
ADAM metallopeptidase domain 19b
Symbol
adam19b Nomenclature History
Previous Names
  • si:dkeyp-44a8.1
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Predicted to act upstream of or within proteolysis. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Is expressed in nervous system. Orthologous to human ADAM19 (ADAM metallopeptidase domain 19).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Cox et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Cox et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adam19b Human Ortholog
No data available
Associated With adam19b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018358 Disintegrin, conserved site
Domain IPR000742 EGF-like domain
Domain IPR001590 Peptidase M12B, ADAM/reprolysin
Domain IPR001762 Disintegrin domain
Domain IPR002870 Peptidase M12B, propeptide
Domain IPR006586 ADAM, cysteine-rich domain
Domain IPR034027 Reprolysin domain, adamalysin-type
Family IPR033596 ADAM19 peptidase
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR036436 Disintegrin domain superfamily
Domain Details Per Protein
Protein Length ADAM19 peptidase ADAM, cysteine-rich domain Disintegrin, conserved site Disintegrin domain Disintegrin domain superfamily EGF-like domain Metallopeptidase, catalytic domain superfamily Peptidase M12B, ADAM/reprolysin Peptidase M12B, propeptide Reprolysin domain, adamalysin-type
UniProtKB:F1QK73 155
UniProtKB:F1Q4N9 923
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations