ZFIN is now using GRCz12tu for Genomic Data
Gene
nrxn2a
- ID
- ZDB-GENE-070206-5
- Name
- neurexin 2a
- Symbol
- nrxn2a Nomenclature History
- Previous Names
-
- nrxn2aa
- nrxn2ab
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable neuroligin family protein binding activity and transmembrane signaling receptor activity. Acts upstream of or within chemical synaptic transmission and motor neuron axon guidance. Predicted to be located in membrane. Predicted to be part of trans-synaptic protein complex. Predicted to be active in presynaptic active zone membrane. Is expressed in nervous system and spinal cord neural tube. Orthologous to human NRXN2 (neurexin 2).
- Genome Resources
- Note
-
nrxn2a has two isoforms, alpha (DQ641428) and beta (DQ641429)
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR003585 | Neurexin/syndecan/glycophorin C |
| Domain | IPR027789 | Syndecan/Neurexin domain |
| Family | IPR050372 | Neurexin-related cell adhesion and synaptic protein |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
Domain Details Per Protein
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nrxn2a-201
(1)
|
Ensembl | 4,333 nt | ||
| mRNA |
nrxn2a-203
(1)
|
Ensembl | 6,930 nt | ||
| mRNA |
nrxn2a-204
(1)
|
Ensembl | 5,013 nt | ||
| ncRNA |
nrxn2a-003
(1)
|
Ensembl | 576 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers