ZFIN is now using GRCz12tu for Genomic Data
Gene
sirt3
- ID
- ZDB-GENE-070112-1762
- Name
- sirtuin 3
- Symbol
- sirt3 Nomenclature History
- Previous Names
-
- zgc:158774
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable NAD+ binding activity and histone deacetylase activity, NAD-dependent. Predicted to be active in nucleus. Is expressed in liver and retina. Orthologous to human SIRT3 (sirtuin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR026590 | Sirtuin family, catalytic core domain |
| Family | IPR003000 | Sirtuin family |
| Family | IPR017328 | Sirtuin, class I |
| Family | IPR050134 | NAD-dependent sirtuin protein deacylases |
| Homologous_superfamily | IPR026591 | Sirtuin, catalytic core small domain superfamily |
| Homologous_superfamily | IPR029035 | DHS-like NAD/FAD-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | DHS-like NAD/FAD-binding domain superfamily | NAD-dependent sirtuin protein deacylases | Sirtuin, catalytic core small domain superfamily | Sirtuin, class I | Sirtuin family | Sirtuin family, catalytic core domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B4G2 | InterPro | 253 | ||||||
| UniProtKB:A0A2R8QMP7 | InterPro | 358 | ||||||
| UniProtKB:A0A8M6Z7Q0 | InterPro | 204 | ||||||
| UniProtKB:A1L2B7 | InterPro | 357 | ||||||
| UniProtKB:A0AB32TXB8 | InterPro | 153 | ||||||
| UniProtKB:A0AB32TZP1 | InterPro | 252 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers