Gene
f2rl1.1
- ID
- ZDB-GENE-061215-140
- Name
- coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
- Symbol
- f2rl1.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and respiratory allergy. Orthologous to human F2RL1 (F2R like trypsin receptor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Alsrhani et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Protease-activated receptor | Protease-activated receptor 2 |
|---|---|---|---|---|---|
|
UniProtKB:A1A5V5
|
380 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
f2rl1.1-201
(1)
|
Ensembl | 1,641 nt | ||
| mRNA |
f2rl1.1-202
(1)
|
Ensembl | 879 nt |
Interactions and Pathways
No data available
Plasmids
No data available