Gene
serpinf2b
- ID
- ZDB-GENE-061215-114
- Name
- serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
- Symbol
- serpinf2b Nomenclature History
- Previous Names
-
- zgc:158410
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in COVID-19 and alpha-2-plasmin inhibitor deficiency. Orthologous to human SERPINF2 (serpin family F member 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
alpha-2-plasmin inhibitor deficiency | Alliance | Alpha-2-plasmin inhibitor deficiency | 262850 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR023795 | Serpin, conserved site |
Domain | IPR023796 | Serpin domain |
Domain | IPR033833 | Alpha2-antiplasmin, serpin domain |
Family | IPR000215 | Serpin family |
Homologous_superfamily | IPR036186 | Serpin superfamily |
Homologous_superfamily | IPR042178 | Serpin superfamily, domain 1 |
Homologous_superfamily | IPR042185 | Serpin superfamily, domain 2 |
Domain Details Per Protein
Protein | Length | Alpha2-antiplasmin, serpin domain | Serpin, conserved site | Serpin domain | Serpin family | Serpin superfamily | Serpin superfamily, domain 1 | Serpin superfamily, domain 2 |
---|---|---|---|---|---|---|---|---|
UniProtKB:A1A5Y8
|
479 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
serpinf2b-201
(1)
|
Ensembl | 1,803 nt | ||
mRNA |
serpinf2b-202
(1)
|
Ensembl | 623 nt | ||
mRNA |
serpinf2b-203
(1)
|
Ensembl | 1,712 nt |
Interactions and Pathways
No data available
Plasmids
No data available