Gene

dkk3b

ID
ZDB-GENE-061207-74
Name
dickkopf WNT signaling pathway inhibitor 3b
Symbol
dkk3b Nomenclature History
Previous Names
  • dkk3
  • si:dkey-80c24.6
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have co-receptor binding activity and receptor antagonist activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to localize to extracellular space. Is expressed in posterior pancreatic bud. Orthologous to human DKK3 (dickkopf WNT signaling pathway inhibitor 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Chiang et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dkk3b Human Ortholog
No data available
Associated With dkk3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006796 Dickkopf, N-terminal cysteine-rich
Domain IPR047300 Dickkopf-related protein 3, second cysteine-rich domain
Domain IPR047301 Dickkopf-related protein 3, N-terminal domain
Family IPR039863 Dickkopf related protein 1-4
Domain Details Per Protein
Protein Length Dickkopf, N-terminal cysteine-rich Dickkopf related protein 1-4 Dickkopf-related protein 3, N-terminal domain Dickkopf-related protein 3, second cysteine-rich domain
UniProtKB:A2CEU2 283
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dkk3b-201 (1) Ensembl 1,118 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations