Gene

dkk3b

ID

ZDB-GENE-061207-74

Name

dickkopf WNT signaling pathway inhibitor 3b

Symbol

dkk3b Nomenclature History

Previous Names

dkk3
si:dkey-80c24.6

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have co-receptor binding activity and receptor antagonist activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to localize to extracellular space. Is expressed in posterior pancreatic bud. Orthologous to human DKK3 (dickkopf WNT signaling pathway inhibitor 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Chiang et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dkk3b Human Ortholog

No data available

Associated With dkk3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006796	Dickkopf, N-terminal cysteine-rich
Domain	IPR047300	Dickkopf-related protein 3, second cysteine-rich domain
Domain	IPR047301	Dickkopf-related protein 3, N-terminal domain
Family	IPR039863	Dickkopf related protein 1-4