Gene
bcl11ba
- ID
- ZDB-GENE-061207-62
- Name
- BCL11 transcription factor B a
- Symbol
- bcl11ba Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in thymus. Human ortholog(s) of this gene implicated in immunodeficiency 49. Orthologous to human BCL11B (BCL11 transcription factor B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 49 | Alliance | Immunodeficiency 49, severe combined | 617237 |
| Intellectual developmental disorder with dysmorphic facies, speech delay, and T-cell abnormalities | 618092 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Developmental and Hematopoietic Transcription Factors | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
|
UniProtKB:A0A2R8Q8A6
|
814 | |||
|
UniProtKB:A0A8M3AR85
|
813 | |||
|
UniProtKB:X1WBZ3
|
776 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
bcl11ba-202
(1)
|
Ensembl | 1,065 nt | ||
| mRNA |
bcl11ba-203
(1)
|
Ensembl | 3,240 nt | ||
| mRNA |
bcl11ba-204
(1)
|
Ensembl | 6,099 nt | ||
| mRNA |
bcl11ba-205
(1)
|
Ensembl | 8,016 nt | ||
| ncRNA |
bcl11ba-003
(1)
|
Ensembl | 543 nt |
Interactions and Pathways
No data available
Plasmids
No data available