Gene
ap1b1
- ID
- ZDB-GENE-061025-1
- Name
- adaptor related protein complex 1 subunit beta 1
- Symbol
- ap1b1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have clathrin binding activity. Involved in several processes, including detection of mechanical stimulus involved in sensory perception; regulation of sodium ion transmembrane transporter activity; and sensory organ development. Predicted to localize to clathrin adaptor complex. Is expressed in brain; eye; female organism; inner ear; and otic vesicle. Orthologous to human AP1B1 (adaptor related protein complex 1 subunit beta 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Keratitis-ichthyosis-deafness syndrome, autosomal recessive | 242150 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002553 | Clathrin/coatomer adaptor, adaptin-like, N-terminal |
| Domain | IPR008152 | Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain |
| Domain | IPR015151 | Beta-adaptin appendage, C-terminal subdomain |
| Family | IPR016342 | AP-1/2/4 complex subunit beta |
| Family | IPR026739 | AP complex subunit beta |
| Homologous_superfamily | IPR009028 | Coatomer/calthrin adaptor appendage, C-terminal subdomain |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR012295 | TBP domain superfamily |
| Homologous_superfamily | IPR013037 | Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain |
| Homologous_superfamily | IPR013041 | Clathrin adaptor, appendage, Ig-like subdomain superfamily |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Repeat | IPR000225 | Armadillo |
Domain Details Per Protein
| Protein | Length | AP-1/2/4 complex subunit beta | AP complex subunit beta | Armadillo | Armadillo-like helical | Armadillo-type fold | Beta-adaptin appendage, C-terminal subdomain | Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain | Clathrin adaptor, appendage, Ig-like subdomain superfamily | Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain | Clathrin/coatomer adaptor, adaptin-like, N-terminal | Coatomer/calthrin adaptor appendage, C-terminal subdomain | TBP domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A5PMT0
|
124 | ||||||||||||
|
UniProtKB:A0A2R8Q6M9
|
976 | ||||||||||||
|
UniProtKB:A5PMS9
|
947 | ||||||||||||
|
UniProtKB:A0A2R8QRX3
|
952 |
Interactions and Pathways
No data available
Plasmids
No data available