Gene

smc5

ID
ZDB-GENE-061013-288
Name
structural maintenance of chromosomes 5
Symbol
smc5 Nomenclature History
Previous Names
  • pufa (1)
  • pum3
  • wu:fb70d10
  • wu:fi47h05
  • zgc:152845
  • zgc:66377
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have ATP binding activity. Predicted to be involved in double-strand break repair via homologous recombination and sister chromatid cohesion. Predicted to localize to Smc5-Smc6 complex and nucleus. Orthologous to human SMC5 (structural maintenance of chromosomes 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Zhu et al., 2023
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Zhu et al., 2023
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With smc5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Atelis syndrome 2 620185
Associated With smc5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003395 RecF/RecN/SMC, N-terminal
Domain IPR038729 Rad50/SbcC-type AAA domain
Family IPR027131 Structural maintenance of chromosomes protein 5
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Rad50/SbcC-type AAA domain RecF/RecN/SMC, N-terminal Structural maintenance of chromosomes protein 5
UniProtKB:F1QEQ8 697
UniProtKB:E7F0W1 1073
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA smc5-201 (1) Ensembl 2,447 nt
mRNA smc5-202 (1) Ensembl 3,966 nt
mRNA smc5-203 (1) Ensembl 1,384 nt
mRNA smc5-206 (1) Ensembl 3,831 nt
ncRNA smc5-002 (1) Ensembl 788 nt
ncRNA smc5-003 (1) Ensembl 731 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations