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ZIRC
ZFIN ID: ZDB-GENE-061013-24
Gene Name: mitochondrial calcium uniporter
Gene Symbol: mcu
Sequence Ontology ID : SO:0000704

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Previous Names: ccdc109a, wu:fi24a01, zgc:153607 (1)

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits identical protein binding activity. Involved in several processes, including actin filament organization; calcium import into the mitochondrion; and convergent extension involved in  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ct149aGt Transgenic Insertion Unknown Unknown DNA
la027461Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22206 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tpl124 Small Deletion Unknown Unknown CRISPR
    Targeting reagents:
    DISEASE ASSOCIATED WITH mcu HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mcu VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process calcium import into the mitochondrion (more)
    Cellular Component integral component of mitochondrial inner membrane (more)
    Molecular Function identical protein binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006769 (1)
  • InterPro:IPR039055 (1)
  • Pfam:PF04678 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mcu-201 (1) 1323
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mcu No data available
    MARKER RELATIONSHIPS
    mcuContained in: [BAC] CH73-57A19 (1) (order this)
    [Fosmid] CH1073-92F7 (1) (order this), CH1073-423J5 (1) (order this), ZFOS-289A11 (1)
    mcuEncodes: [EST] fi24a01
    [cDNA] MGC:153607 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077325 (1) 1898bp
    Genomic GenBank:CU856520 (1) 108204bp
    Select Tool
    Polypeptide UniProtKB:F1QT29 (1) 376aa
    Sequence Clusters UniGene:122221 (1)
    Sequence Information (all 25)
    ORTHOLOGY for mcu (Chr: 13)
    CITATIONS (32)