Gene

cenpe

ID

ZDB-GENE-060929-860

Name

centromere protein E

Symbol

cenpe Nomenclature History

Previous Names

wu:fc06a10
zgc:152925 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have ATP-dependent microtubule motor activity, plus-end-directed and microtubule binding activity. Predicted to be involved in microtubule-based movement and mitotic cell cycle. Predicted to localize to microtubule. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 13. Orthologous to human CENPE (centromere protein E).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cenpe Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
primary autosomal recessive microcephaly 13	Alliance	?Microcephaly 13, primary, autosomal recessive	616051

Associated With cenpe Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019821	Kinesin motor domain, conserved site
Domain	IPR001752	Kinesin motor domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily

Domain Details Per Protein

Protein	Length	Kinesin motor domain	Kinesin motor domain, conserved site	Kinesin motor domain superfamily	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:F1RDY0 InterPro	317
UniProtKB:F1R0G3 InterPro	170
UniProtKB:F1QUW6 InterPro	199
UniProtKB:Q08CM3 InterPro	317
UniProtKB:F1R7B6 InterPro	171
UniProtKB:E7F2U4 InterPro	2690

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	cenpe-202 (1) Ensembl	8469 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	cenpe-203 (1) Ensembl	514 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	cenpe-205 (1) Ensembl	509 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	cenpe-206 (1) Ensembl	942 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	cenpe-003 (1) Ensembl	534 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations