Gene
cenpe
- ID
- ZDB-GENE-060929-860
- Name
- centromere protein E
- Symbol
- cenpe Nomenclature History
- Previous Names
-
- wu:fc06a10
- zgc:152925 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable microtubule binding activity. Predicted to be involved in microtubule-based movement and mitotic cell cycle. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in microtubule. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 13. Orthologous to human CENPE (centromere protein E).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Yu et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary autosomal recessive microcephaly 13 | Alliance | ?Microcephaly 13, primary, autosomal recessive | 616051 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019821 | Kinesin motor domain, conserved site |
| Domain | IPR001752 | Kinesin motor domain |
| Family | IPR027640 | Kinesin-like protein |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Kinesin-like protein | Kinesin motor domain | Kinesin motor domain, conserved site | Kinesin motor domain superfamily | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6YXU4 | InterPro | 2352 | |||||
| UniProtKB:A0A8M2BFG2 | InterPro | 2668 | |||||
| UniProtKB:E7F2U4 | InterPro | 2690 | |||||
| UniProtKB:A0A8M2BFG4 | InterPro | 2626 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available