Gene

adam28

ID
ZDB-GENE-060929-532
Name
ADAM metallopeptidase domain 28
Symbol
adam28 Nomenclature History
Previous Names
  • si:ch211-133n22.1
  • zgc:153755
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Is predicted to enable endopeptidase activity and metallopeptidase activity. Acts upstream of or within integrin-mediated signaling pathway and proteolysis. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human ADAM28 (ADAM metallopeptidase domain 28).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adam28 Human Ortholog
No data available
Associated With adam28 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018358 Disintegrin, conserved site
Domain IPR000742 EGF-like domain
Domain IPR001590 Peptidase M12B, ADAM/reprolysin
Domain IPR001762 Disintegrin domain
Domain IPR002870 Peptidase M12B, propeptide
Domain IPR006586 ADAM, cysteine-rich domain
Domain IPR034027 Reprolysin domain, adamalysin-type
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR036436 Disintegrin domain superfamily
Domain Details Per Protein
Protein Length ADAM, cysteine-rich domain Disintegrin, conserved site Disintegrin domain Disintegrin domain superfamily EGF-like domain Metallopeptidase, catalytic domain superfamily Peptidase M12B, ADAM/reprolysin Peptidase M12B, propeptide Reprolysin domain, adamalysin-type
UniProtKB:A3KQJ0 762
UniProtKB:Q08C21 293
UniProtKB:A0A2R8QP33 286
UniProtKB:A0A2R8QJX9 293
UniProtKB:A0A2R8QF72 293
UniProtKB:F1QDC4 765
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations