Gene
lratb.1
- ID
- ZDB-GENE-060810-31
- Name
- lecithin retinol acyltransferase b, tandem duplicate 1
- Symbol
- lratb.1 Nomenclature History
- Previous Names
-
- lratb
- im:7148552
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Enables phosphatidylcholine-retinol O-acyltransferase activity. Acts upstream of or within retinol metabolic process. Predicted to be located in membrane. Predicted to be active in rough endoplasmic reticulum. Is expressed in several structures, including central nervous system; hindbrain neural keel; margin; mesoderm; and neural crest. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 14 and retinitis pigmentosa. Orthologous to human LRAT (lecithin retinol acyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7148552 (21 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Isken et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Leber congenital amaurosis 14 | Alliance | Leber congenital amaurosis 14 | 613341 |
| Leber congenital amaurosis 14 | Alliance | Retinal dystrophy, early-onset severe | 613341 |
| Leber congenital amaurosis 14 | Alliance | Retinitis pigmentosa, juvenile | 613341 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Length |
|---|---|
|
UniProtKB:A0A8M9Q803
|
642 |
|
UniProtKB:A0A0R4IX64
|
679 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lratb.1-201
(1)
|
Ensembl | 998 nt |
Interactions and Pathways
No data available
Plasmids
No data available