Gene

arhgef15b

ID
ZDB-GENE-060810-103
Name
Rho guanine nucleotide exchange factor 15b
Symbol
arhgef15b Nomenclature History
Previous Names
  • im:7158374 (1)
  • si:dkey-38p12.3
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of actin cytoskeleton organization. Orthologous to human ARHGEF15 (Rho guanine nucleotide exchange factor 15).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa6251Allele with one point mutationUnknownPremature StopENU
sa22088Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa35285Allele with one point mutationUnknownSplice SiteENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With arhgef15b Human Ortholog
No data available
Associated With arhgef15b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000219 Dbl homology domain
Domain IPR001452 SH3 domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR047270 Ephexin-like, PH domain
Family IPR047271 Ephexin-like
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Domain Details Per Protein
Protein Additional Resources Length Dbl homology (DH) domain superfamily Dbl homology domain Ephexin-like Ephexin-like, PH domain PH-like domain superfamily Pleckstrin homology domain SH3 domain SH3-like domain superfamily
UniProtKB:A0A8M9Q0N9 InterPro 867
UniProtKB:A0A8M3BE83 InterPro 937
UniProtKB:A0A8M9PTG7 InterPro 937
UniProtKB:A0A8M9PX10 InterPro 867
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 12
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:dkey-38p12.3-201 (1)
Ensembl
Ensembl 4,238 nt
ZFIN BLAST
mRNA si:dkey-38p12.3-202 (1)
Ensembl
Ensembl 4,799 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-38P12ZFIN Curated Data
EncodesESTIMAGE:7158374Thisse et al., 2004
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_678013 (1)4241 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:AL929346 (1)184825 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A8M3BE83 (1)937 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Species Symbol Chromosome Accession # Evidence
HumanARHGEF1517
Phylogenetic tree (1)
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseArhgef1511
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Phylogenetic tree (1)
Citations
TSV
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