ZFIN is now using GRCz12tu for Genomic Data
Gene
stra6
- ID
- ZDB-GENE-060616-252
- Name
- signaling receptor and transporter of retinol STRA6
- Symbol
- stra6 Nomenclature History
- Previous Names
-
- im:7151282
- wu:fc51h06
- zgc:136689 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables calmodulin binding activity and molecular adaptor activity. Acts upstream of or within chordate embryonic development and retinol transport. Located in plasma membrane. Is expressed in several structures, including hindbrain neural plate; immature eye; nervous system; pleuroperitoneal region; and trunk. Used to study syndromic microphthalmia 9. Human ortholog(s) of this gene implicated in syndromic microphthalmia 9. Orthologous to human STRA6 (signaling receptor and transporter of retinol STRA6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151282 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Isken et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| syndromic microphthalmia 9 | Alliance | Microphthalmia, isolated, with coloboma 8 | 601186 |
| syndromic microphthalmia 9 | Alliance | Microphthalmia, syndromic 9 | 601186 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR026612 | Receptor for retinol uptake STRA6-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | Receptor for retinol uptake STRA6-like |
|---|---|---|---|
| UniProtKB:A0A8M9PGX1 | InterPro | 670 | |
| UniProtKB:F1RAX4 | InterPro PDB | 670 | |
| UniProtKB:A0AC58IW06 | InterPro | 670 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers