Gene

stra6

ID
ZDB-GENE-060616-252
Name
signaling receptor and transporter of retinol STRA6
Symbol
stra6 Nomenclature History
Previous Names
  • im:7151282
  • wu:fc51h06
  • zgc:136689 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Exhibits calmodulin binding activity and identical protein binding activity. Involved in chordate embryonic development and retinol transport. Localizes to integral component of plasma membrane. Used to study Matthew-Wood syndrome. Human ortholog(s) of this gene implicated in Matthew-Wood syndrome. Is expressed in several structures, including hindbrain neural plate; immature eye; nervous system; pleuroperitoneal region; and trunk. Orthologous to human STRA6 (signaling receptor and transporter of retinol STRA6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Isken et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With stra6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
syndromic microphthalmia 9 Alliance Microphthalmia, isolated, with coloboma 8 601186
syndromic microphthalmia 9 Alliance Microphthalmia, syndromic 9 601186
Associated With stra6 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR026612 Receptor for retinol uptake STRA6
Domain Details Per Protein
Protein Length Receptor for retinol uptake STRA6
UniProtKB:F1RAX4 670
UniProtKB:Q6DGZ6 238
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations