Gene

stra6

ID
ZDB-GENE-060616-252
Name
signaling receptor and transporter of retinol STRA6
Symbol
stra6 Nomenclature History
Previous Names
  • im:7151282
  • wu:fc51h06
  • zgc:136689 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Exhibits calmodulin binding activity and identical protein binding activity. Involved in chordate embryonic development and retinol transport. Localizes to integral component of plasma membrane. Is expressed in several structures, including hindbrain neural plate; immature eye; nervous system; pleuroperitoneal region; and trunk. Used to study syndromic microphthalmia 9. Human ortholog(s) of this gene implicated in syndromic microphthalmia 9. Orthologous to human STRA6 (signaling receptor and transporter of retinol STRA6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Isken et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With stra6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
syndromic microphthalmia 9 Alliance Microphthalmia, isolated, with coloboma 8 601186
syndromic microphthalmia 9 Alliance Microphthalmia, syndromic 9 601186
Associated With stra6 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR026612 Receptor for retinol uptake STRA6-like
Domain Details Per Protein
Protein Length Receptor for retinol uptake STRA6-like
UniProtKB:A0A8M9PGX1 670
UniProtKB:F1RAX4 670
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA stra6-201 (1) Ensembl 2,888 nt
mRNA stra6-203 (1) Ensembl 2,290 nt
mRNA stra6-204 (1) Ensembl 2,972 nt
ncRNA stra6-002 (1) Ensembl 523 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations