Gene
stra6
- ID
- ZDB-GENE-060616-252
- Name
- signaling receptor and transporter of retinol STRA6
- Symbol
- stra6 Nomenclature History
- Previous Names
-
- im:7151282
- wu:fc51h06
- zgc:136689 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Exhibits calmodulin binding activity and identical protein binding activity. Involved in chordate embryonic development and retinol transport. Localizes to integral component of plasma membrane. Is expressed in several structures, including hindbrain neural plate; immature eye; nervous system; pleuroperitoneal region; and trunk. Used to study syndromic microphthalmia 9. Human ortholog(s) of this gene implicated in syndromic microphthalmia 9. Orthologous to human STRA6 (signaling receptor and transporter of retinol STRA6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151282 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Isken et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| syndromic microphthalmia 9 | Alliance | Microphthalmia, isolated, with coloboma 8 | 601186 |
| syndromic microphthalmia 9 | Alliance | Microphthalmia, syndromic 9 | 601186 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR026612 | Receptor for retinol uptake STRA6-like |
Domain Details Per Protein
| Protein | Length | Receptor for retinol uptake STRA6-like |
|---|---|---|
|
UniProtKB:A0A8M9PGX1
|
670 | |
|
UniProtKB:F1RAX4
|
670 |
Interactions and Pathways
No data available
Plasmids
No data available