Gene

sftpbb

ID

ZDB-GENE-060526-155

Name

surfactant protein Bb

Symbol

sftpbb Nomenclature History

Previous Names

si:ch211-283h6.6
wu:fd19f07

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to be located in cytoplasm and extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in lung disease (multiple); respiratory syncytial virus infectious disease; and toxic shock syndrome. Orthologous to human SFTPB (surfactant protein B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sftpbb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
pulmonary alveolar proteinosis	Alliance	Surfactant metabolism dysfunction, pulmonary, 1	265120

Associated With sftpbb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR007856	Saposin-like type B, region 1
Domain	IPR008138	Saposin B type, region 2
Domain	IPR008139	Saposin B type domain
Domain	IPR013087	Zinc finger C2H2-type
Family	IPR008373	Saposin
Family	IPR051428	Sphingolipid Activators and Surfactant Proteins
Homologous_superfamily	IPR011001	Saposin-like