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General Information
ZIRC
ZFIN ID: ZDB-GENE-060512-359
Gene Name: TANK-binding kinase 1
Gene Symbol: tbk1
Sequence Ontology ID : SO:0000704

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Previous Names: wu:fk70c05, zgc:136548 (1)

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene  ...
GENE EXPRESSION
All Expression Data: 2 figures from GarcĂ­a-Valtanen et al., 2017
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa29267 Point Mutation Unknown Missense, Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tbk1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
FTDALS4 Frontotemporal dementia and/or amyotrophic lateral sclerosis 4 616439
{Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 8} 617900
DISEASE ASSOCIATED WITH tbk1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Cellular Component cytoplasm (more)
Molecular Function protein binding (more)
GO Terms (all 11)
TRANSCRIPTS
Type Name Length (bp) Analysis
ncRNA tbk1-002 (1) 1702
tbk1-003 (1) 2125
tbk1-004 (1) 722
mRNA tbk1-201 (1) 3115
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM tbk1 No data available
MARKER RELATIONSHIPS
tbk1Contained in: [Fosmid] CH1073-90P17 (1) (order this), CH1073-190H2 (1) (order this)
tbk1Encodes: [EST] fk70c05
[cDNA] MGC:136548 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001044748 (1) 1736bp
Genomic GenBank:FP245483 (1) 35135bp
Select Tool
Polypeptide UniProtKB:Q0GKD6 (1) 727aa
Sequence Clusters UniGene:82024 (1)
Sequence Information (all 26)
ORTHOLOGY for tbk1 (Chr: 4)
CITATIONS (26)