Gene
exosc5
- ID
- ZDB-GENE-060503-675
- Name
- exosome component 5
- Symbol
- exosc5 Nomenclature History
- Previous Names
-
- si:ch211-194n6.2
- zgc:153707
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to be involved in RNA metabolic process. Predicted to localize to cytoplasmic exosome (RNase complex); nuclear exosome (RNase complex); and nucleolus. Orthologous to human EXOSC5 (exosome component 5).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Cabrera-Quio et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Slavotinek et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Cerebellar ataxia, brain abnormalities, and cardiac conduction defects | 619576 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001247 | Exoribonuclease, phosphorolytic domain 1 |
Domain | IPR015847 | Exoribonuclease, phosphorolytic domain 2 |
Family | IPR050080 | Ribonuclease PH |
Homologous_superfamily | IPR020568 | Ribosomal protein uS5 domain 2-type superfamily |
Homologous_superfamily | IPR027408 | PNPase/RNase PH domain superfamily |
Homologous_superfamily | IPR036345 | Exoribonuclease, PH domain 2 superfamily |
Domain Details Per Protein
Protein | Length | Exoribonuclease, PH domain 2 superfamily | Exoribonuclease, phosphorolytic domain 1 | Exoribonuclease, phosphorolytic domain 2 | PNPase/RNase PH domain superfamily | Ribonuclease PH | Ribosomal protein uS5 domain 2-type superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M1NAS6
|
230 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
exosc5-201
(1)
|
Ensembl | 705 nt | ||
mRNA |
exosc5-202
(1)
|
Ensembl | 486 nt |
Interactions and Pathways
No data available
Plasmids
No data available