Gene

slc9a3.2

ID
ZDB-GENE-060503-640
Name
solute carrier family 9 member A3, tandem duplicate 2
Symbol
slc9a3.2 Nomenclature History
Previous Names
  • nhe3b (1)
  • si:dkey-3n22.6
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Exhibits sodium:proton antiporter activity. Involved in ammonium transmembrane transport; sodium ion homeostasis; and sodium ion import across plasma membrane. Localizes to apical plasma membrane. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 8. Is expressed in gill; integument; and renal system. Orthologous to human SLC9A3 (solute carrier family 9 member A3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
24 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc9a3.2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital secretory sodium diarrhea 8 Alliance Diarrhea 8, secretory sodium, congenital 616868
Associated With slc9a3.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006153 Cation/H+ exchanger
Family IPR004709 Na+/H+ exchanger
Family IPR018410 Na+/H+ exchanger, isoforms 3/5
Family IPR018422 Cation/H+ exchanger, CPA1 family
Domain Details Per Protein
Protein Length Cation/H+ exchanger Cation/H+ exchanger, CPA1 family Na+/H+ exchanger Na+/H+ exchanger, isoforms 3/5
UniProtKB:A3KPJ8 851
UniProtKB:A9XP97 851
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-slc9a3.2 polyclonal Rat
  • IHC
2
Ab2-slc9a3.2 polyclonal Rabbit
  • IHC
  • WB
1
Ab4-slc9a3.2 Rabbit
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations