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General Information
ZIRC
ZFIN ID: ZDB-GENE-060421-4031
Gene Name: interferon regulatory factor 1a
Gene Symbol: irf1a
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: IRF11 (1), irf1 (1), zgc:136945

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in immune system process. Predicted to localize to the nucleus. Human ortholog(s) of  ...
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb134 Small Deletion Exon 1 Frameshift, Premature Stop CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb194 Insertion Exon 1 Unknown CRISPR
    Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH irf1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    lung cancer Nonsmall cell lung cancer, somatic 211980
    stomach cancer Gastric cancer, somatic 613659
    Myelogenous leukemia, acute
    Myelodysplastic syndrome, preleukemic
    DISEASE ASSOCIATED WITH irf1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA irf1a-201 (1) 1439
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM irf1a No data available
    MARKER RELATIONSHIPS
    irf1aContained in: [Fosmid] ZFOS-1762D12 (1)
    irf1aEncodes: [cDNA] MGC:136945 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001040352 (1) 1480bp
    Genomic GenBank:CU694274 (1) 41491bp
    Select Tool
    Polypeptide UniProtKB:F1QPF2 (1) 251aa
    Sequence Clusters UniGene:81011 (1)
    Sequence Information (all 13)
    ORTHOLOGY for irf1a (Chr: 13)
    CITATIONS (35)