Gene
rtn2b
- ID
- ZDB-GENE-060331-95
- Name
- reticulon 2b
- Symbol
- rtn2b Nomenclature History
- Previous Names
-
- rtn8 (1)
- zgc:136618
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 12. Is expressed in skeletal muscle. Orthologous to human RTN2 (reticulon 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Housley et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 12 | Alliance | Spastic paraplegia 12, autosomal dominant | 604805 |
| Neuronopathy, distal hereditary motor, autosomal recessive 11, with spasticity | 620854 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Reticulon | Reticulon 1-4 |
|---|---|---|---|
|
UniProtKB:Q4G5T7
|
208 | ||
|
UniProtKB:A0A8M9PQI6
|
204 | ||
|
UniProtKB:A0A8M2B839
|
161 |
Interactions and Pathways
No data available
Plasmids
No data available