Gene
rac1b
- ID
- ZDB-GENE-060312-45
- Name
- Rac family small GTPase 1b
- Symbol
- rac1b Nomenclature History
- Previous Names
-
- zgc:136799
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including Ras protein signal transduction; engulfment of apoptotic cell; and motor neuron axon guidance. Predicted to localize to several cellular components, including cell cortex; cytoplasmic vesicle; and cytoskeleton. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 48; colon adenocarcinoma; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Epting et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 48 | Alliance | Intellectual developmental disorder, autosomal dominant 48 | 617751 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTPase Rho | Small GTP-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q29RC5
|
192 |
Interactions and Pathways
No data available
Plasmids
No data available