ZFIN is now using GRCz12tu for Genomic Data
Gene
plag1
- ID
- ZDB-GENE-060302-2
- Name
- pleiomorphic adenoma gene 1
- Symbol
- plag1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Is expressed in several structures, including axial vasculature; head; head mesenchyme; immature eye; and ventricular zone. Human ortholog(s) of this gene implicated in Silver-Russell syndrome and pleomorphic adenoma. Orthologous to human PLAG1 (PLAG1 zinc finger).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Pendeville et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pleomorphic adenoma | Alliance | Adenomas, salivary gland pleomorphic, somatic | 181030 |
| Silver-Russell syndrome 4 | 618907 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
| UniProtKB:Q29YB2 | InterPro | 393 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers