Gene
dact2
- ID
- ZDB-GENE-030131-9975
- Name
- dishevelled-binding antagonist of beta-catenin 2
- Symbol
- dact2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Involved in negative regulation of nodal signaling pathway. Acts upstream of or within Wnt signaling pathway and mesoderm morphogenesis. Predicted to be located in late endosome; nucleus; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including blastodisc; brain; digestive system; germ ring; and mesoderm. Used to study bile duct carcinoma; pancreatic carcinoma; and retinitis pigmentosa. Orthologous to human DACT2 (dishevelled binding antagonist of beta catenin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR024843 | Dapper |
Domain Details Per Protein
| Protein | Length | Dapper |
|---|---|---|
|
UniProtKB:F1RE13
|
837 | |
|
UniProtKB:Q673G8
|
837 |
Interactions and Pathways
No data available
Plasmids