Gene
dgat2
- ID
- ZDB-GENE-050913-15
- Name
- diacylglycerol O-acyltransferase 2
- Symbol
- dgat2 Nomenclature History
- Previous Names
-
- zgc:113394
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable diacylglycerol O-acyltransferase activity. Acts upstream of or within lipid homeostasis; regulation of response to endoplasmic reticulum stress; and response to (R)-carnitine. Predicted to be located in lipid droplet and perinuclear endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in intestine and male organism. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease. Orthologous to human DGAT2 (diacylglycerol O-acyltransferase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from O'Hare et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR007130 | Diacylglycerol acyltransferase |
Domain Details Per Protein
| Protein | Length | Diacylglycerol acyltransferase |
|---|---|---|
|
UniProtKB:Q4V9F0
|
361 |
Interactions and Pathways
No data available
Plasmids