Gene

camk2g1

ID

ZDB-GENE-050913-146

Name

calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1

Symbol

camk2g1 Nomenclature History

Previous Names

camk2ga
zgc:109908

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Exhibits calmodulin-dependent protein kinase activity. Involved in animal organ development and protein autophosphorylation. Predicted to localize to cytoplasm and neuron projection. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Is expressed in several structures, including gut; nervous system; neural tube; notochord; and pronephric duct. Orthologous to human CAMK2G (calcium/calmodulin dependent protein kinase II gamma).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

15 figures from 8 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:109908 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 19 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With camk2g1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Intellectual developmental disorder, autosomal dominant 59	618522

Associated With camk2g1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR013543	Calcium/calmodulin-dependent protein kinase II, association-domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR032710	NTF2-like domain superfamily

Domain Details Per Protein

Protein	Length	Calcium/calmodulin-dependent protein kinase II, association-domain	NTF2-like domain superfamily	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site
UniProtKB:A0A8M2B2D8 InterPro	624
UniProtKB:A0A8M9QEF1 InterPro	595
UniProtKB:Q4V9P8 InterPro	560
UniProtKB:A0A8M2B2F0 InterPro	574
UniProtKB:A0A8M2B384 InterPro	522
UniProtKB:A0A8M3BEA7 InterPro	577
UniProtKB:A0A8M2B2F7 InterPro	493
UniProtKB:A0A8M2B2P8 InterPro	606
UniProtKB:A0A8M2B379 InterPro	598
UniProtKB:A0A8M2B2E6 InterPro	627
UniProtKB:A0A8M9QIV6 InterPro	517
UniProtKB:A0A8M2B341 InterPro	581
UniProtKB:A0A8M2B346 InterPro	514
UniProtKB:A0A8M2B2Q2 InterPro	543
UniProtKB:A0A8M9QMM9 InterPro	578
UniProtKB:A0A8M2B2E5 InterPro	546

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	camk2g1-201 (1) Ensembl	Ensembl	4,445 nt	Select Tool
mRNA	camk2g1-202 (1) Ensembl	Ensembl	636 nt	Select Tool
mRNA	camk2g1-204 (1) Ensembl	Ensembl	1,219 nt	Select Tool
ncRNA	camk2g1-002 (1) Ensembl	Ensembl	1,097 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations