Gene
camk2g1
- ID
- ZDB-GENE-050913-146
- Name
- calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
- Symbol
- camk2g1 Nomenclature History
- Previous Names
-
- camk2ga
- zgc:109908
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Enables calcium/calmodulin-dependent protein kinase activity. Involved in pronephros structural organization. Acts upstream of or within several processes, including heart jogging; inner ear receptor cell differentiation; and protein autophosphorylation. Predicted to be active in cytoplasm; neuron projection; and postsynaptic density. Is expressed in several structures, including gut; nervous system; neural tube; notochord; and pronephric duct. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 59. Orthologous to human CAMK2G (calcium/calmodulin dependent protein kinase II gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109908 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 19 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 59 | Alliance | Intellectual developmental disorder, autosomal dominant 59 | 618522 |
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Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR013543 | Calcium/calmodulin-dependent protein kinase II, association-domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
1 - 5 of 6 Show all
Domain Details Per Protein
| Protein | Additional Resources | Length | Calcium/calmodulin-dependent protein kinase II, association-domain | NTF2-like domain superfamily | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B2D8 | InterPro | 624 | ||||||
| UniProtKB:A0A8M9QEF1 | InterPro | 595 | ||||||
| UniProtKB:Q4V9P8 | InterPro | 560 | ||||||
| UniProtKB:A0A8M2B2F0 | InterPro | 574 | ||||||
| UniProtKB:A0A8M2B384 | InterPro | 522 |
1 - 5 of 19 Show all
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
camk2g1-201
(1)
|
Ensembl | 4,445 nt | ||
| mRNA |
camk2g1-202
(1)
|
Ensembl | 636 nt | ||
| mRNA |
camk2g1-204
(1)
|
Ensembl | 1,219 nt | ||
| ncRNA |
camk2g1-002
(1)
|
Ensembl | 1,097 nt |
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Interactions and Pathways
No data available
Plasmids
No data available