ZFIN is now using GRCz12tu for Genomic Data
Gene
ctbp2l
- ID
- ZDB-GENE-050902-1
- Name
- C-terminal binding protein 2, like
- Symbol
- ctbp2l Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor binding activity; transcription coregulator activity; and transcription coregulator binding activity. Acts upstream of or within clustering of voltage-gated calcium channels and synapse assembly involved in innervation. Located in basolateral plasma membrane. Is expressed in otic vesicle and sensory system. Orthologous to human CTBP2 (C-terminal binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 22 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Sheets et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR029753 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site |
| Domain | IPR006139 | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain |
| Domain | IPR006140 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain |
| Family | IPR043322 | C-terminal binding protein |
| Family | IPR051638 | C-terminal-binding dehydrogenase |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C-terminal-binding dehydrogenase | C-terminal binding protein | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site | NAD(P)-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q5BU17 | InterPro | 860 | ||||||
| UniProtKB:A0AC58GZC4 | InterPro | 862 | ||||||
| UniProtKB:A0AC58GZC9 | InterPro | 862 | ||||||
| UniProtKB:A0AC58GZD1 | InterPro | 406 | ||||||
| UniProtKB:A0AC58GZD3 | InterPro | 406 | ||||||
| UniProtKB:A0AC58GZD4 | InterPro | 886 | ||||||
| UniProtKB:A0AC58GZD5 | InterPro | 406 | ||||||
| UniProtKB:A0AC58GZD8 | InterPro | 430 | ||||||
| UniProtKB:A0AC58GZE0 | InterPro | 430 | ||||||
| UniProtKB:A0AC58GZE1 | InterPro | 501 | ||||||
| UniProtKB:A0AC58GZE2 | InterPro | 430 | ||||||
| UniProtKB:A0AC58GZE4 | InterPro | 416 | ||||||
| UniProtKB:A0AC58GZF3 | InterPro | 886 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ctbp2l-201
(1)
|
Ensembl | 1,593 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-ctbp2l | polyclonal | Rabbit |
|
12 | |||
| Ab4-ctbp2l | polyclonal | Rabbit |
|
Proteintech
|
3 | ||
| Ab3-ctbp2l | monoclonal | Mouse |
|
15 | |||
| Ab2-ctbp2l | polyclonal | Rabbit |
|
7 |
Plasmids
No data available
- Genome Browsers