Gene
ezrb
- ID
- ZDB-GENE-050803-1
- Name
- ezrin b
- Symbol
- ezrb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable actin binding activity and cell adhesion molecule binding activity. Acts upstream of or within several processes, including cell migration involved in gastrulation; epiboly; and regulation of cilium assembly. Predicted to be located in several cellular components, including apical plasma membrane; cell cortex; and cell projection membrane. Predicted to be active in several cellular components, including adherens junction; filopodium; and microvillus. Is expressed in several structures, including anterior axial hypoblast; digestive system; hatching gland; nervous system; and prechordal plate. Orthologous to human EZR (ezrin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb567 (14 images)
- IMAGE:7140274 (13 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019747 | FERM conserved site |
| Domain | IPR000299 | FERM domain |
| Domain | IPR011259 | Ezrin/radixin/moesin, C-terminal |
| Domain | IPR018979 | FERM, N-terminal |
| Domain | IPR018980 | FERM, C-terminal PH-like domain |
| Domain | IPR019748 | FERM central domain |
| Domain | IPR019749 | Band 4.1 domain |
| Domain | IPR041789 | ERM family, FERM domain C-lobe |
| Domain | IPR046810 | Ezrin/radixin/moesin, alpha-helical domain |
| Family | IPR000798 | Ezrin/radixin/moesin-like |
| Family | IPR011174 | Ezrin/radixin/moesin |
| Homologous_superfamily | IPR008954 | Moesin tail domain superfamily |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR014352 | FERM/acyl-CoA-binding protein superfamily |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR035963 | FERM superfamily, second domain |
Domain Details Per Protein
| Protein | Additional Resources | Length | Band 4.1 domain | ERM family, FERM domain C-lobe | Ezrin/radixin/moesin | Ezrin/radixin/moesin, alpha-helical domain | Ezrin/radixin/moesin, C-terminal | Ezrin/radixin/moesin-like | FERM/acyl-CoA-binding protein superfamily | FERM central domain | FERM conserved site | FERM, C-terminal PH-like domain | FERM domain | FERM, N-terminal | FERM superfamily, second domain | Moesin tail domain superfamily | PH-like domain superfamily | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q5TZG5 | InterPro | 583 |
Interactions and Pathways
No data available
Plasmids
No data available