Gene
amh
- ID
- ZDB-GENE-050706-192
- Name
- anti-Mullerian hormone
- Symbol
- amh Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have growth factor activity. Involved in negative regulation of androgen secretion and sperm capacitation. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in disorders of sexual development; ovarian carcinoma; and persistent Mullerian duct syndrome. Is expressed in female organism; granulosa cell; male organism; and reproductive system. Orthologous to human AMH (anti-Mullerian hormone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 66 figures from 49 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| persistent Mullerian duct syndrome | Alliance | Persistent Mullerian duct syndrome, type I | 261550 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Anti-Mullerian hormone, N-terminal | Cystine-knot cytokine | Muellerian-inhibiting factor | Transforming growth factor-beta, C-terminal |
|---|---|---|---|---|---|
|
UniProtKB:A8E7B8
|
549 | ||||
|
UniProtKB:Q6B6Q2
|
549 |
Interactions and Pathways
No data available
Plasmids