Gene

amh

ID
ZDB-GENE-050706-192
Name
anti-Mullerian hormone
Symbol
amh Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have growth factor activity. Involved in negative regulation of androgen secretion and sperm capacitation. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in disorders of sexual development; ovarian carcinoma; and persistent Mullerian duct syndrome. Is expressed in female organism; granulosa cell; male organism; and reproductive system. Orthologous to human AMH (anti-Mullerian hormone).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
65 figures from 48 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
17 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With amh Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
persistent Mullerian duct syndrome Alliance Persistent Mullerian duct syndrome, type I 261550
Associated With amh Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001839 Transforming growth factor-beta, C-terminal
Domain IPR006799 Anti-Mullerian hormone, N-terminal
Family IPR021203 Muellerian-inhibiting factor
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Anti-Mullerian hormone, N-terminal Cystine-knot cytokine Muellerian-inhibiting factor Transforming growth factor-beta, C-terminal
UniProtKB:A8E7B8 549
UniProtKB:Q6B6Q2 549
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA amh-201 (1) Ensembl 3,243 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-amh Rabbit
  • IHC
1
Ab1-amh Rabbit
1
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations