Gene

amh

ID
ZDB-GENE-050706-192
Name
anti-Mullerian hormone
Symbol
amh Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to enable growth factor activity. Acts upstream of or within development of primary sexual characteristics; negative regulation of androgen secretion; and sperm capacitation. Predicted to be located in extracellular region. Is expressed in female organism; granulosa cell; male organism; and reproductive system. Human ortholog(s) of this gene implicated in disorder of sexual development; ovarian carcinoma; and persistent Mullerian duct syndrome. Orthologous to human AMH (anti-Mullerian hormone).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
52 figures from 35 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With amh Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
persistent Mullerian duct syndrome Alliance Persistent Mullerian duct syndrome, type I 261550
Associated With amh Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001839 Transforming growth factor-beta, C-terminal
Domain IPR006799 Anti-Mullerian hormone, N-terminal
Family IPR021203 Muellerian-inhibiting factor
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Anti-Mullerian hormone, N-terminal Cystine-knot cytokine Muellerian-inhibiting factor Transforming growth factor-beta, C-terminal
UniProtKB:Q50D78 549
UniProtKB:A8E7B8 549
UniProtKB:Q6B6Q2 549
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-amh Rabbit
  • IHC
1
Ab1-amh Rabbit
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations