Gene
amh
- ID
- ZDB-GENE-050706-192
- Name
- anti-Mullerian hormone
- Symbol
- amh Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable growth factor activity. Acts upstream of or within several processes, including negative regulation of androgen secretion; regulation of ovarian follicle development; and sperm capacitation. Predicted to be located in extracellular region. Is expressed in female organism; granulosa cell; male organism; and reproductive system. Human ortholog(s) of this gene implicated in disorder of sexual development; ovarian carcinoma; and persistent Mullerian duct syndrome. Orthologous to human AMH (anti-Mullerian hormone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 68 figures from 51 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| persistent Mullerian duct syndrome | Alliance | Persistent Mullerian duct syndrome, type I | 261550 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Anti-Mullerian hormone, N-terminal | Cystine-knot cytokine | Muellerian-inhibiting factor | Transforming growth factor-beta, C-terminal |
|---|---|---|---|---|---|---|
| UniProtKB:A8E7B8 | InterPro | 549 | ||||
| UniProtKB:Q6B6Q2 | InterPro | 549 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids