ZFIN is now using GRCz12tu for Genomic Data
Gene
mlx
- ID
- ZDB-GENE-050522-316
- Name
- MAX dimerization protein MLX
- Symbol
- mlx Nomenclature History
- Previous Names
-
- im:7146242
- TF4 (1)
- wu:fb61a01
- wu:fb99c01
- zgc:112409
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Takayasu's arteritis. Orthologous to human MLX (MAX dimerization protein MLX).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7146242 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Weger et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Helix-loop-helix DNA-binding domain superfamily | Max-like/E-box-binding transcription factors | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|---|---|
| UniProtKB:A0A8M1N6M0 | InterPro | 247 | |||
| UniProtKB:A0A8M1P225 | InterPro | 246 | |||
| UniProtKB:A0A8M6Z577 | InterPro | 252 | |||
| UniProtKB:A0A8M6YYM7 | InterPro | 253 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers