Gene

lims1

ID

ZDB-GENE-050522-236

Name

LIM and senescent cell antigen-like domains 1

Symbol

lims1 Nomenclature History

Previous Names

pinch1 (1)
wu:fc32c03
zgc:112533

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have metal ion binding activity. Involved in heart contraction and regulation of protein kinase B signaling. Localizes to Z disc and intercalated disc. Is expressed in EVL; hatching gland; heart; periderm; and polster. Orthologous to human LIMS1 (LIM zinc finger domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:112533 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Meder et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lims1 Human Ortholog

No data available

Associated With lims1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001781	Zinc finger, LIM-type
Domain	IPR047944	LIMS1/2-like, LIM domain 1
Family	IPR047946	LIM and senescent cell antigen-like-containing domain protein 1/2-like