Gene

sncgb

ID

ZDB-GENE-050522-235

Name

synuclein, gamma b (breast cancer-specific protein 1)

Symbol

sncgb Nomenclature History

Previous Names

Sncg1 (1)
sncg
sncga (1)
zgc:112131
zSyn-γ1 (1)
zSynA (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Involved in dopaminergic neuron differentiation and larval locomotory behavior. Human ortholog(s) of this gene implicated in Lewy body dementia. Is expressed in basal plate midbrain region; gill; nervous system; testis; and trigeminal placode. Orthologous to human SNCG (synuclein gamma).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

20 figures from 9 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7159885 (14 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Milanese et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sncgb Human Ortholog

No data available

Associated With sncgb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR001058	Synuclein

Domain Details Per Protein

Protein	Length	Synuclein
UniProtKB:A0A8M9PWC8 InterPro	120
UniProtKB:Q502J6 InterPro	114

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	sncgb-201 (1) Ensembl	Ensembl		856 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-sncgb	polyclonal	sncgb		Rabbit	WB		2

Plasmids

Addgene:PCRII-zSynA

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations