ZFIN is now using GRCz12tu for Genomic Data
Gene
fitm2
- ID
- ZDB-GENE-050508-5
- Name
- fat storage inducing transmembrane protein 2
- Symbol
- fitm2 Nomenclature History
- Previous Names
-
- fit2
- c20orf142
- wu:fc04g08
- wu:fr13b05
- zgc:110840 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable coenzyme A diphosphatase activity; diacylglycerol binding activity; and triglyceride binding activity. Acts upstream of or within several processes, including glucose homeostasis; pancreas regeneration; and type B pancreatic cell development. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adaxial cell and slow muscle cell. Human ortholog(s) of this gene implicated in Siddiqi syndrome. Orthologous to human FITM2 (fat storage inducing transmembrane protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7154803 (5 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Siddiqi syndrome | Alliance | Siddiqi syndrome | 618635 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Fat storage-inducing transmembrane protein | Fat storage-inducing transmembrane protein 1/2 |
|---|---|---|---|---|
| UniProtKB:Q52KL1 | InterPro | 252 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers