Gene

fat1a

ID
ZDB-GENE-050425-1
Name
FAT atypical cadherin 1a
Symbol
fat1a Nomenclature History
Previous Names
  • fat1
  • fat
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Involved in pronephros development. Predicted to localize to membrane. Is expressed in several structures, including digestive system; nervous system; otic vesicle; pleuroperitoneal region; and tail bud. Orthologous to human FAT1 (FAT atypical cadherin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa494Allele with one point mutationUnknownPremature StopENU
sa1140Allele with one point mutationUnknownPremature StopENU
sa1599Allele with one point mutationUnknownPremature StopENU
sa12774Allele with one point mutationUnknownSplice SiteENU
sa13483Allele with one point mutationUnknownPremature StopENU
sa14711Allele with one point mutationUnknownPremature StopENU
sa24837Allele with one point mutationUnknownPremature StopENU
sa25555Allele with one point mutationUnknownPremature StopENU
sa32637Allele with one point mutationUnknownPremature StopENU
sa38253Allele with one point mutationUnknownPremature StopENU
1 - 10 of 14
Show
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-fat1a
    Lahrouchi et al., 2019
    MO1-fat1aN/A (2)
    MO2-fat1aN/ALahrouchi et al., 2019
    1 - 3 of 3
    Show
    Human Disease
    Associated With fat1a Human Ortholog
    No data available
    Associated With fat1a Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Conserved_site IPR018097 EGF-like calcium-binding, conserved site
    Conserved_site IPR020894 Cadherin conserved site
    Domain IPR000742 EGF-like domain
    Domain IPR001791 Laminin G domain
    Domain IPR001881 EGF-like calcium-binding domain
    1 - 5 of 11 Show all
    Domain Details Per Protein
    Protein Length Cadherin Cadherin conserved site Cadherin-like Cadherin-like superfamily Concanavalin A-like lectin/glucanase domain superfamily EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site Laminin G domain NOTCH1 EGF-like calcium-binding domain
    UniProtKB:A0A8M9PRG7 4666
    UniProtKB:A0A8M9PV49 4643
    UniProtKB:A2BGT8 4611
    UniProtKB:A0A8M2BFN2 4634
    UniProtKB:A0A8M2BG88 4646
    1 - 5 of 5
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 1
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA fat1a-202 (1) Ensembl 16,375 nt
    ncRNA fat1a-002 (1) Ensembl 811 nt
    1 - 2 of 2
    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH211-194C21ZFIN Curated Data
    Contained inBACCH211-197N1ZFIN Curated Data
    Contained inBACDKEY-32G22ZFIN Curated Data
    Contained inBACDKEY-228C11ZFIN Curated Data
    EncodesESTeu651Thisse et al., 2005
    1 - 5 of 5
    Show
    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanFAT14
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    MouseFat18
    Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Citations
    1 - 10 of 15
    Show