Gene
kif3a
- ID
- ZDB-GENE-050417-71
- Name
- kinesin family member 3A
- Symbol
- kif3a Nomenclature History
- Previous Names
-
- fc55h04
- wu:fc55h04
- zgc:110284
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Acts upstream of or within several processes, including hematopoietic progenitor cell differentiation; photoreceptor cell maintenance; and photoreceptor cell outer segment organization. Part of kinesin complex. Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region. Orthologous to human KIF3A (kinesin family member 3A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 28 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la012523Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| ouc2004 | Allele with one deletion | Exon 4 | Premature Stop | CRISPR | |
| pd1084 | Allele with one point mutation | Unknown | Splicing Variant | ENU | |
| sa1617 | Allele with one point mutation | Exon 9 | Premature Stop | ENU |
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| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-kif3a | (3) | |
| CRISPR2-kif3a | Xie et al., 2022 | |
| CRISPR3-kif3a | Xie et al., 2022 | |
| MO1-kif3a | N/A | (3) |
| MO2-kif3a | N/A | Khan et al., 2016 |
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Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019821 | Kinesin motor domain, conserved site |
| Domain | IPR001752 | Kinesin motor domain |
| Family | IPR027640 | Kinesin-like protein |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Kinesin-like protein | Kinesin motor domain | Kinesin motor domain, conserved site | Kinesin motor domain superfamily | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|
| UniProtKB:E9QB71 | InterPro | 701 | |||||
| UniProtKB:A0A8M9QB16 | InterPro | 436 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-20F11 | ZFIN Curated Data | |
| Encodes | EST | fc55h04 | ||
| Encodes | cDNA | MGC:110284 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192509 | ZFIN Curated Data |
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