Gene
iscub
- ID
- ZDB-GENE-050417-332
- Name
- iron-sulfur cluster assembly enzyme b
- Symbol
- iscub Nomenclature History
- Previous Names
-
- fj08f02
- wu:fj08f02
- zgc:110331
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have 2 iron, 2 sulfur cluster binding activity; 4 iron, 4 sulfur cluster binding activity; and ferrous iron binding activity. Predicted to be involved in cellular iron ion homeostasis. Predicted to localize to mitochondrial matrix. Orthologous to human ISCU (iron-sulfur cluster assembly enzyme).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Myopathy with lactic acidosis, hereditary | 255125 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Iron-sulfur cluster assembly scaffold protein IscU | NIF system FeS cluster assembly, NifU, N-terminal |
|---|---|---|---|
|
UniProtKB:Q568F2
|
164 | ||
|
UniProtKB:F1QM53
|
164 |
Interactions and Pathways
No data available
Plasmids
No data available