Gene

frg1

ID
ZDB-GENE-050417-324
Name
FSHD region gene 1
Symbol
frg1 Nomenclature History
Previous Names
  • zgc:112426
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable actin filament binding activity. Predicted to be located in Cajal body and Z disc. Predicted to be part of catalytic step 2 spliceosome. Predicted to be active in nucleolus and striated muscle dense body. Orthologous to human FRG1 (FSHD region gene 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa39578Allele with one point mutationUnknownPremature StopENU
zko320aAllele with one deletionUnknownUnknownCRISPR
zko320bAllele with one deletionUnknownUnknownCRISPR
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Sequence Targeting Reagents
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Human Disease
Associated With frg1 Human Ortholog
No data available
Associated With frg1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR010414 Protein FRG1
Homologous_superfamily IPR008999 Actin-crosslinking
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Domain Details Per Protein
Protein Additional Resources Length Actin-crosslinking Protein FRG1
UniProtKB:Q566W5 InterPro 255
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 1
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript frg1-204 (1) Ensembl 816 nt
mRNA frg1-201 (1) Ensembl 1,154 nt
mRNA frg1-203 (1) Ensembl 426 nt
mRNA frg1-205 (1) Ensembl 2,707 nt
ncRNA frg1-004 (1) Ensembl 881 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-7C14ZFIN Curated Data
Contained inBACDKEYP-88C1ZFIN Curated Data
EncodescDNAMGC:112426ZFIN Curated Data
EncodescDNAMGC:174670ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanFRG14
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseFrg18
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
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