Gene
hapln1a
- ID
- ZDB-GENE-050302-175
- Name
- hyaluronan and proteoglycan link protein 1a
- Symbol
- hapln1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable hyaluronic acid binding activity. Acts upstream of or within extracellular matrix organization involved in endocardium development and fin regeneration. Predicted to be located in plasma membrane. Predicted to be active in extracellular space; perineuronal net; and synapse. Is expressed in several structures, including adaxial cell; cardiovascular system; hypochord; pharyngeal arch; and rhombomere. Orthologous to human HAPLN1 (hyaluronan and proteoglycan link protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Derrick et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000538 | Link domain |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Family | IPR050691 | Hyaluronan-binding Proteoglycan |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
| Homologous_superfamily | IPR016187 | C-type lectin fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | C-type lectin fold | C-type lectin-like/link domain superfamily | Hyaluronan-binding Proteoglycan | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain | Link domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q1LXE1
|
336 | |||||||||
|
UniProtKB:B3DIH3
|
328 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hapln1a-201
(1)
|
Ensembl | 585 nt | ||
| mRNA |
hapln1a-202
(1)
|
Ensembl | 4,922 nt | ||
| mRNA |
hapln1a-203
(1)
|
Ensembl | 4,877 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-HAPLN1a | polyclonal | Rabbit |
|
Proteintech
|
1 |
Plasmids
No data available