Gene

hif1al2

ID
ZDB-GENE-050211-2
Name
hypoxia inducible factor 1 subunit alpha, like 2
Symbol
hif1al2 Nomenclature History
Previous Names
  • hif1al (1)
  • Hif2a (1)
  • HIF3B (1)
  • zgc:112119
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in cellular response to hypoxia and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including digestive system; gill; head; heart; and pleuroperitoneal region.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hif1al2 Human Ortholog
No data available
Associated With hif1al2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000014 PAS domain
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Domain IPR013655 PAS fold-3
Domain IPR013767 PAS fold
Domain IPR014887 HIF-1 alpha, transactivation domain, C-terminal
Family IPR021537 Hypoxia-inducible factor, alpha subunit
Homologous_superfamily IPR035965 PAS domain superfamily
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Repeat IPR001610 PAC motif
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily HIF-1 alpha, transactivation domain, C-terminal Hypoxia-inducible factor, alpha subunit Myc-type, basic helix-loop-helix (bHLH) domain PAC motif PAS domain PAS domain superfamily PAS fold PAS fold-3
UniProtKB:Q567E1 660
UniProtKB:Q5I9I8 523
UniProtKB:F1QQQ1 663
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
ab1-hif1al2 polyclonal Rabbit
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations