ZFIN ID: ZDB-GENE-050208-99
Gene Name: PHD finger protein 21Aa
Gene Symbol: phf21aa    Nomenclature History

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Previous Names: im:7138823 (1), si:dkey-23n7.9

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have chromatin binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to histone deacetylase complex. Is expressed in central nervous system and neural plate. Orthologous to human PHF21A (PHD finger protein 21A).
Genome Resources: Alliance (1),  Gene:497383 (1),  Ensembl(GRCz11):ENSDARG00000006878 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2004 [IMAGE:7138823]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
aik4 Small Deletion Exon 6 Unknown CRISPR
sa2379 Point Mutation Unknown Splice Site ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-phf21aa 1
MO1-phf21aa N/A 1
PHENOTYPE
Data: Fig. 1 from Mishoe et al., 2019
Observed in:
DISEASE ASSOCIATED WITH phf21aa HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without seizures 618725
DISEASE ASSOCIATED WITH phf21aa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of transcription by RNA polymerase II (more)
Cellular Component histone deacetylase complex (more)
Molecular Function chromatin binding (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA phf21aa-201 (1)    Ensembl 4994
phf21aa-204 (1)    Ensembl 5144
phf21aa-205 (1)    Ensembl 5078
ncRNA phf21aa-003 (1)    Ensembl 836
phf21aa-004 (1)    Ensembl 212
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM phf21aa No data available
MARKER RELATIONSHIPS
phf21aa Contained in: [BAC] DKEY-23N7 (1) (order this)
phf21aa Encodes: [EST] IMAGE:7138823 (1)
phf21aa Has Artifact: [EST] fc69h08
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001328015 (1)
Genomic GenBank:BX957256 (1) 227909 nt Blast at MegaBLAST
Polypeptide UniProtKB:A0A1D5NSS3 (1) 686 aa
Sequence Information (all 19)
ORTHOLOGY for phf21aa ( Chr: 7 )
CITATIONS (19)