Gene
foxo3a
- ID
- ZDB-GENE-050116-1
- Name
- forkhead box O3A
- Symbol
- foxo3a Nomenclature History
- Previous Names
-
- fb50g02
- fi33f07
- wu:fb50g02
- wu:fi33f07
- zgc:92176
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of nervous system development and regulation of neuron apoptotic process. Predicted to colocalize with mitochondrial matrix. Is expressed in several structures, including brain; digestive system; eye; pericardial region; and pleuroperitoneal region. Orthologous to human FOXO3 (forkhead box O3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Peng et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR030456 | Fork head domain conserved site 2 |
Domain | IPR001766 | Fork head domain |
Domain | IPR032067 | FOXO protein, transactivation domain |
Domain | IPR032068 | FOXO protein, KIX-binding domain |
Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Fork head domain | Fork head domain conserved site 2 | FOXO protein, KIX-binding domain | FOXO protein, transactivation domain | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:Q5I0F7
|
643 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
foxo3a-201
(1)
|
5649 nt |
Interactions and Pathways
No data available
Plasmids
No data available