Gene

spx

ID
ZDB-GENE-041210-158
Name
spexin hormone
Symbol
spx Nomenclature History
Previous Names
  • si:dkey-13i19.7 (1)
  • spexin
  • SPX1 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable neuropeptide hormone activity; type 2 galanin receptor binding activity; and type 3 galanin receptor binding activity. Involved in cholesterol homeostasis; glucose homeostasis; and triglyceride homeostasis. Acts upstream of or within negative regulation of eating behavior. Located in nucleus. Is expressed in several structures, including central nervous system; heart; liver; male organism; and pleuroperitoneal region. Orthologous to human SPX (spexin hormone).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Zheng et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spx Human Ortholog
No data available
Associated With spx Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR028126 Spexin
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations