Gene

lin7c

ID
ZDB-GENE-041011-2
Name
lin-7 homolog C (C. elegans)
Symbol
lin7c Nomenclature History
Previous Names
  • fb75b09
  • wu:fb75b09
  • zgc:101881
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits L27 domain binding activity. Involved in maintenance of epithelial cell apical/basal polarity. Predicted to localize to MPP7-DLG1-LIN7 complex; basolateral plasma membrane; and synapse. Is expressed in several structures, including eye; neural rod; neural tube; neuroepithelial cell; and optic vesicle. Orthologous to human LIN7C (lin-7 homolog C, crumbs cell polarity complex component).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Yang et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lin7c Human Ortholog
No data available
Associated With lin7c Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001478 PDZ domain
Domain IPR004172 L27 domain
Domain IPR014775 L27 domain, C-terminal
Family IPR017365 Protein lin-7
Family IPR051109 Membrane-associated multiprotein complex regulator
Homologous_superfamily IPR036034 PDZ superfamily
Homologous_superfamily IPR036892 L27 domain superfamily
Domain Details Per Protein
Protein Length L27 domain L27 domain, C-terminal L27 domain superfamily Membrane-associated multiprotein complex regulator PDZ domain PDZ superfamily Protein lin-7
UniProtKB:Q66IB0 201
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lin7c-201 (1) Ensembl 4,301 nt
mRNA lin7c-202 (1) Ensembl 1,523 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-lin7 polyclonal Rabbit
  • IHC
  • WB
6
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations