Gene
gpd1l
- ID
- ZDB-GENE-041010-220
- Name
- glycerol-3-phosphate dehydrogenase 1 like
- Symbol
- gpd1l Nomenclature History
- Previous Names
-
- wu:fi13g03
- wu:fi45b08
- zgc:92580
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have NAD binding activity; glycerol-3-phosphate dehydrogenase [NAD+] activity; and protein homodimerization activity. Predicted to be involved in carbohydrate metabolic process; glycerol-3-phosphate catabolic process; and oxidation-reduction process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Orthologous to human GPD1L (glycerol-3-phosphate dehydrogenase 1 like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92580 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Brugada syndrome 2 | Alliance | Brugada syndrome 2 | 611777 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006109 | Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal |
| Domain | IPR011128 | Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal |
| Family | IPR006168 | Glycerol-3-phosphate dehydrogenase, NAD-dependent |
| Family | IPR017751 | Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic |
| Homologous_superfamily | IPR008927 | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily |
| Homologous_superfamily | IPR013328 | 6-phosphogluconate dehydrogenase, domain 2 |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | 6-phosphogluconate dehydrogenase, domain 2 | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily | Glycerol-3-phosphate dehydrogenase, NAD-dependent | Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal | Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic | Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal | NAD(P)-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5XIZ6
|
351 |
Interactions and Pathways
No data available
Plasmids
No data available