ZFIN ID: ZDB-GENE-040905-2
Gene Name: transcription factor 25 (basic helix-loop-helix)
Gene Symbol: tcf25    Nomenclature History

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Previous Name: zgc:101131 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in lens; mesoderm; notochord; and somite. Orthologous to human TCF25 (transcription factor 25).
Genome Resources: Alliance (1),  Gene:445817 (1),  Ensembl(GRCz11):ENSDARG00000040861 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:101131]
  6 figures (13 images) from Thisse et al., 2004 [IMAGE:7157357]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23323 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tcf25 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tcf25 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of transcription by RNA polymerase II (more)
    Cellular Component nucleus (more)
    Molecular Function DNA-binding transcription factor activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tcf25-202 (1)    Ensembl 2184
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tcf25 No data available
    MARKER RELATIONSHIPS
    tcf25 Contained in: [BAC] CH211-132F3 (1), CH211-220F20 (1)
    tcf25 Encodes: [EST] IMAGE:7157357 (1)
    [cDNA] MGC:101131 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001005399 (1) 2250 nt
    Genomic GenBank:CR457484 (1) 169672 nt
    Select Tool
    Polypeptide UniProtKB:Q1L887 (1) 650 aa
    Sequence Information (all 14)
    ORTHOLOGY for tcf25 ( Chr: 18 )
    CITATIONS (22)