Gene
dnaaf11
- ID
- ZDB-GENE-040827-2
- Name
- dynein axonemal assembly factor 11
- Symbol
- dnaaf11 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Involved in several processes, including cilium movement involved in cell motility; embryonic morphogenesis; and motile cilium assembly. Localizes to cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 19. Is expressed in several structures, including floor plate; forerunner cell group; olfactory pit; pronephros; and tail bud. Orthologous to human LRRC6 (leucine rich repeat containing 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 20 figures from 9 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 19 | Alliance | Ciliary dyskinesia, primary, 19 | 614935 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Leucine-rich repeat | Leucine-rich repeat domain superfamily |
|---|---|---|---|
|
UniProtKB:F1Q7C0
|
440 | ||
|
UniProtKB:B3DH20
|
440 |
Interactions and Pathways
No data available
Plasmids
No data available