Gene

ift172

ID
ZDB-GENE-040827-1
Name
intraflagellar transport 172
Symbol
ift172 Nomenclature History
Previous Names
  • moe (1)
  • LIM-interacting protein (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Involved in several processes, including animal organ development; photoreceptor cell maintenance; and regulation of TOR signaling. Predicted to localize to axoneme; ciliary basal body; and intraciliary transport particle B. Used to study cystic kidney disease. Human ortholog(s) of this gene implicated in retinitis pigmentosa 71 and short-rib thoracic dysplasia 10 with or without polydactyly. Orthologous to human IFT172 (intraflagellar transport 172).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
23 figures from 15 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ift172 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Bardet-Biedl syndrome 20 Alliance Bardet-Biedl syndrome 20 619471
retinitis pigmentosa 71 Alliance Retinitis pigmentosa 71 616394
short-rib thoracic dysplasia 10 with or without polydactyly Alliance Short-rib thoracic dysplasia 10 with or without polydactyly 615630
Associated With ift172 Via Experimental Models
Human Disease Fish Conditions Citations
cystic kidney disease li1Tg + MO3-ift172 control Pandey et al., 2019
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Tetratricopeptide-like helical domain superfamily WD40 repeat WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:B3DK94 1745
UniProtKB:Q5RHH4 1745
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations